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Sensing of viral and endogenous RNA by ZBP 1/DAI induces necroptosis

Lung tissue is considered the primary target organ for inhaled ultrafine particles

Moreover, also the core clock component BMAL1 has been reported to bind to p53 promoter, thereby transcriptionally triggering the downstream tumor suppressor pathway 37

Schweitzer, R., Zelzer, E

After the treatment of rabbits with these medication, the protein expression of CYP11A1 was slightly down-regulated in both livers and testes except Sildenafil up-regulated such protein expression