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Additionally, polymorphisms in the AKR1B1 gene, which encodes aldose reductase and is involved in the metabolic pathways of diabetic complications, are significantly associated with the risk of retinopathy in diabetic patients

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Store unopened vials at -20C (freezer) and reconstituted solutions at 2-8C (refrigerator) for optimal stability and shelf life

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Interestingly the compounds with gallate groups showed higher toxicity in comparison to those same compounds without gallate groups (Ugartondo et al