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doi: 10.3389/fanim.2025.1713884 Received 23 October 2025 Revised 25 November 2025 Accepted 28 November 2025 Published 17 December 2025 Volume 6 - 2025 Edited by Wellison J

Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival

Sun H, Cai H, Xu C, Zhai H, Lux F, Xie Y, Feng L, Du L, Liu Y, Sun X, et al

[Araliaceae] and Panax notoginseng (Burkill) F.H.Chen [Araliaceae], preserves mitochondrial membrane potential by inhibiting CYP2E1, thereby preventing cytochrome c release and apoptosis (Yang et al., 2021a)