cellular glutathione and thiols metabolism Its Implications for Health The Role of Glutathione Metabolism

doi: 10.3389/fcimb.2026.1752304 Received 23 November 2025 Revised 12 January 2026 Accepted 31 January 2026 Published 19 February 2026 Volume 16 - 2026 Edited by Teclegiorgis Gebremariam, Lundquist Institute for Biomedical Innovation, United States Reviewed by Fatemeh Ahangarkani, 4cyte Pathology, Australia Sanam Dolati, Lundquist Institute for Biomedical Innovation, United States Updates Copyright 2026 Wu, Jiang, Wang, Chen, Chen and Da

Researchers have noted that an impaired redox balanceprimarily a deficiency of NAD+ and GSHis a main feature of NAFLD

Given that 70% of Mel and 85% of insulin-stimulated glucose disposal enters the skeletal muscle, the enhancement of insulin sensitivity and glucose balance by MOTS-c may be mediated in this tissue

In a case-control study Khurana et al

MR scan assessors were blinded to participant group allocation