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[51] Additionally, "[p]ostmortem examinations of human tissues have linked use of the drug to diseases associated with aging, such as coronary atherosclerosis and pulmonary fibrosis", [52] which may be caused "by a considerable rise in the formation of ceramides, pro-inflammatory molecules that can foster cell aging and death." [52] Dental and oral health ("meth mouth") Methamphetamine users, particularly heavy users, may lose their teeth abnormally quickly, regardless of the route of administration, from a condition informally known as meth mouth

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Metabolic-to-epigenetic modulation is considered to be one of the main reasons for the therapeutic effect of KD in neurodevelopmental disorders

Some patients achieve doubledigit percentage weight loss over several months when medication is combined with lifestyle changes