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511 Mitophagy diminishes insoluble A 1-42 , A 1-40 , and hyper-phosphorylated tau, preventing cognitive or memory impairment in mouse model

Thus, research interest has focused on the development of early detection techniques via monitoring saliva, serum, CSF, neuroimaging biomarkers, and cognitive dysfunction [31]

Vesicomyid clam habitats in cold seeps can also enable a higher degree of macrofaunal diversity than what could be expected purely from bacterial chemosynthetic activity 67

Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

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