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A recent study reported that egl nine homolog 1 (EGLN1) and Myc activate lymphoid-specific helicase (LSH) expression through HIF-1, and that LSH suppresses ferroptosis through the interaction with WDR76, leading to the activation of lipid metabolism-associated genes (Miess et al., 2018)

If that happens, too much fluid can pool in your belly, legs, and feet, making them swell

Dietary Factors : Highly restrictive diets (e.g., veganism ) may lack adequate B12

For example, changes in bowel habits from anesthesia or pain meds