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Physiol Genomics 29:99108

As weve learned, optimizing B12 therapy means looking at each patients unique needs

f) Safety issues: The safety of the shots is unquestioned if administered from a BD #328438 needle

When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

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