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This work was supported by grants from Instituto Tecnolgico Superior de Ciudad Hidalgo (3308.100310) and Tecnolgico Nacional de Mxico (165.14.2-PD and 166.14.2-PD).

Alongside oestrogen imbalance linked to methylation challenges, we often see low glutathione, increased oxidative stress, and inflammation driving pigmentation

Serum testosterone levels were measured using a testosterone enzyme-linked immunosorbent assay (ELISA) kit (Cusabio biotech, Houston, TX, USA) following the manufacturers instructions

NAC, pycnogenol, cysteine-rich and sulfur-containing foods may be safer options for raising glutathione levels in children

For skin protection and visible anti-aging, astaxanthin has the edge