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In recent years, the development of nanoparticle-based vaccines has benefitted from advances in material science that have led to improvements in antigen structure and stability, targeted vaccine delivery, and immunogenicity with good safety profiles

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Under these conditions, cancer cells highly express glutamine synthetase, facilitating cancer cell growth under radiation stress 150

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Its important to note that even if a molecule possesses the above characteristics, it may not necessarily cross the BBB easily, as the BBB is highly selective, allowing only specific molecules to pass