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Due to its critical and very pleiotropic activity, reduction of BDNF levels and alterations in the BDNF/TrkB signaling are connected with a broad spectrum of neurological diseases

The mushroom plays a role that decomposes lignocellulosic material within forest ecosystems [1]

Upon activation, HSF1 trimers translocate to the nucleus and bind to heat shock elements (HSEs) in the promoters of target genes, thereby increasing the transcription of HSP70s, which then undergo degradation or re-monomerization (Vihervaara and Sistonen, 2014)

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These metabolites exhibit potential therapeutic effects, including antioxidative, anticancer, anti-inflammatory, and antiseptic properties, for various diseases, including liver disorders, neurological conditions, cancer, cardiovascular diseases, and lung diseases, as shown in multiple in vitro and in vivo studies on humans and mice (114, 116, 239)