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Intramuscular Injections: Used for deeper injuries, such as muscle strains

In contrast to quiescence (cell cycle arrest), cellular senescence is a terminal state of growth arrest, where cells cannot re-enter the cell cycle despite mitogenic growth signals (Pack et al., 2019)

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In both cases, a positive effect of EPO was observed, with faster recovery, increased callus formation and vascularization, and higher VEGF expression, as well as ossification and biomechanical strength [134,135]