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Through its reactive sulfhydryl group, GSH participates in oxidation-reduction reactions, thiol-disulfide exchange processes, and cofactor-dependent enzymatic mechanisms

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Manganese superoxide dismutase (MnSOD) is an enzyme belonging to SOD, which is located in the mitochondrial matrix and can remove O 2 generated by energy metabolism, while glutathione peroxidase 1 (GPX1) is the most abundant of the four identified GPX isozymes