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The early presence of OH could help in predicting whether a patient will remain as ILOCA or progress to MSAC

I am 54 years old and had a huge amount of sun damage from living in the sun for almost 20 years, although I dont smoke I had lines around my mouth that looked like I had been smoking my whole life, also I had a large amount of loose skin on my upper eyelids and lines and poor skin around my lower eyes

Lee, E., Lemieux, G., & Mirabbasi, S

The receptor dimer then associates with ERE (Estrogen Receptor Element), this in term recruits and modulates the so-called co-regulatory proteins namely co-activators and co-repressors

Brain Res 710: 229233