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The deep orange hydrocarbon carotene is widely distributed in plants, but is not sufficiently stable to be used as permanent pigment, other than for food coloring

Marnett LJ, Hurd HK, Hollstein MC, Levin DE, Esterbauer H, & Ames BN (1985) Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104

Chronic Inflammation Linked to Metabolic and Heart Disease Chronic inflammation creates a domino effect: It stiffens arteries, triggering high blood pressure and a greater risk of heart attacks and strokes. Cells become more resistant to insulin, making diabetes more likely and harder to control

Kuijper IA, Yang H, Van De Water B, Beltman JB

ABC transporters - The ATP-binding cassette (ABC) protein superfamily is one the largest protein families known, and most, but not all, are membrane proteins (ABC transporters) active in the transport of a broad range of substances across membranes