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doi: 10.1056/NEJM196310102691501 49 Ouled-HaddouH.MessaoudiK.DemontY.SantosR

Instead, it is essential to conduct in-depth analyses of the specific logic of the aforementioned signaling networks in terms of cell types, subcellular compartments, and disease course timings, and clarify their context-dependent controversies to promote the transformation of mechanistic understanding into precision treatment

All treatments of mice in this study were in strict agreement with guidelines on ARRIVE and recommendations from an NIH-sponsored workshop regarding experimental design and reporting standards (41)