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doi: 10.1038/s41380-021-01138-6 215 WaltonC.KingR.RechtmanL.KayeW.LerayE.MarrieR

Additionally, a vitamin B12 deficiency may also lead to other health issues that can result in fatigue, such as megaloblastic anemia

Updated May 15, 2026

435,436 Neuronal injury promotes a neuroinflammatory response, leading to the accumulation of immune cells and the release of inflammatory cytokines, contributing to neuronal hypersensitivity