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GPX1 and 2 are highly expressed in the gastrointestinal epithelium and have been implicated in the development and promotion of colorectal cancer [8]

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Soula M, et al

Genetics Severe elevations of Hcy concentration in plasma is rare and often caused by homozygous mutations in enzymes involved in its metabolism, such as MS, methylene tetrahydrofolate reductase, and CBS