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Additional spontaneous and catalysed O 2 dismutation adds to the net product of H 2 O 2

Traumatic stress upregulated the mRNA expression of corticotropin-releasing factor receptor type 2 (CRFR2) in the bed nucleus of the stria terminalis, which increased the susceptibility of mice to PTSD-like behavior (Lebow et al., 2012)

Iron Requirements of Infants and Toddlers

The transcription factor p53 also plays a dual role in melanocyte defense by upregulating tyrosinase, a key enzyme in melanogenesis, and enhancing the antioxidant response via the Nrf2 pathway 17 , but also it can stop the melanocyte cell cycle, even leading to apoptosis 79

[DOI] [PubMed] [Google Scholar] 24.Jass JR