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Sequence-based drug design as a concept in computational drug design

lvarezJFernndez RealJMGuarnerFGueimondeMRodrguezJMSaenz de PipaonM

First, the dose used in the protocol (1,000 micrograms of methylcobalamin weekly) is far above what a multivitamin provides

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

The phosphorylation can be initiated by a variety of mechanisms that include kinases such as glycogen synthase kinase-3 (GSK-3) and cAMP-dependent protein kinase (PKA) (Gong and Iqbal, 2008)