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According to clinical studies by Natalia et al., antidepressants, including MTZ, are generally safe for patients with epilepsy when used at therapeutic dosages (Grska et al

Zhu, H., Blake, S., Chan, K

Lee, and S.W

Biochemistry of the GST enzymes The fundamental basis for all GST catalytic activities is the capacity of these enzymes to lower the pK a of the sulfhydryl group of reduced glutathione (GSH) from 9.0 in aqueous solution to about 6.5 when GSH is bound in the active site [12]

3.2 Chemical protection In addressing the challenges linked to the vulnerability of physical protection techniques to abrasion degradation, chemical protection approaches, comprising the use of amino acid analogs and their derivatives were developed (Mazinani et al., 2022)