glutathione s transferase alzheimer disease S-transferase: A versatile and dynamic enzyme Glutathione S-Transferase - an overview

Preclinical studies suggest that manipulating SRXN1 activity can modulate oxidative stress levels, reduce cellular damage and improve disease outcomes

This protection is crucial in preventing age-related macular degeneration (AMD), a common eye disease in older adults that can lead to vision loss

Investigators have reported improving the stability of SLNs, drug loading capacity, and targeting capabilities

In DNCB-induced AD mouse model, EGCG-NPs were associated with increased activity of antioxidant enzymes such as SOD and GSH, decreased MDA levels, and enhanced total antioxidant capacity (T-AOC), collectively contributing to the restoration of epidermal redox balance (Han et al., 2022)

Free Radic Biol Med 34:546552 Bjrklund G, Chirumbolo S (2017) Role of oxidative stress and antioxidants in daily nutrition and human health