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Even if virtually, all cell types synthesize GSH, the main source of the tripeptide is liver where the bulk of cysteine, the rate limiting amino acid, derived from diet is metabolized

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In experimental models of SCI, this protein has been found to be significantly elevated for up to 11 months in sensory axons, neurons, astrocytes, and ependymal cells, despite consequent loss of nerve tissue at the site of injury

It has secondary effects through growth mechanisms and patterns, signaling, that create this improvement