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Other important constituents also include several isoflavonoid derivatives such as shinpterocarpin, glabrone, glabridin, galbrene, lico-isoflavones A and B (Asl and Hosseinzadeh, Figure 9 Due to their antioxidative properties, several species of Glycyrrhiza were investigated for possible therapeutic effects as neuroprotectants against neurodegenerative disorders such as PD, AD, and dementia

Notably, the optimal in vivo neuroprotective dose was identified as 0.5 mg/kg, which produced substantial behavioral and histological improvements

Yet, it suggests that the lncRNA SAT1 is crucial for the induction of senescence upon SAL treatment

[CrossRef] [Google Scholar] Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

Although there are some side effects associated with the clinical use of PPAR agents, it is hoped that more effective PPAR-based drugs with fewer side effects will be developed in the future