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Macrophages, particularly the M2 subtype, play a key role in calcific aortic stenosis, and their expression of the pattern recognition receptor Toll-like receptor 7 (TLR7) is associated with inflammation and calcification processes in the aortic valve (265)

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Angle-Closure Glaucoma : The pupillary dilation that occurs following use of many antidepressant drugs including ZOLOFT may trigger an angle closure attack in a patient with anatomically narrow angles who does not have a patent iridectomy