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Diabetologia 59 , 26542663 (2016)

[1] For example, if a 2 mL dose (full 200 mg thiamine, 200 mg niacinamide) is to be given IV, a nurse might mix it into 50 mL of saline and infuse over 15-30 minutes

Systemic Effects Beyond local reactions, some participants in aod 9604 peptide studies report systemic effects: Mild Headaches : Occurring in approximately 5-8% of research subjects, these typically resolve within hours and may be related to initial adaptation to the peptide