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This is chronic inflammation

Symptoms of B12 deficiency include persistent fatigue, weakness, brain fog, mood changes, numbness or tingling in hands and feet, and difficulty concentrating

However, while vitamin B12 is safe when used as recommended, there are several vitamin B12 injection side effects to consider as well

They may also cause side effects such as: nausea and vomiting liver problems increased risk of infection Surgery Doctors may recommend surgery for Crohns, especially if another treatment has not been successful

As to the pain "going in" it may be that the needle caught a nerve or vein plus the fact that you were probably a little tense and nervous