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Results: Compared with strokes due to large artery atherosclerosis, higher PM2.5 and BC levels was significantly associated with cardioembolic stroke (risk ratio per 1-SD increment exposure [95% confidence interval]: PM2.5: 1.36, [1.19-1.56]

The structures show a markedly enlarged polymerase architecture, revealing that CCHFV-L RNA synthesis is accompanied by ordering of the polymerase peripheral domains