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doi: 10.1038/s41392-022-01194-6

Elevated inflammatory markers in these patients correlate with neuroinflammatory changes, microglial activation, and neuronal damage in the hippocampus and prefrontal cortex, leading to persistent cognitive deficits (Sonneville et al., 2023)

They are framed in the guide the way they should be framed: as areas of preclinical research interest that the brand believes are relevant to its product, not as established human clinical outcomes