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( e ) Cells expressing empty vector (EV) or CCNE1 were treated with the IDH1 inhibitor or the PARP inhibitors veliparib (left) or niraparib (right) alone or in combination (n = 4 technical replicates representative from 2 independent experiments in each cell line)

IUPAC [(2R)-3-carboxy-2-(2,2,3,3,3-pentadeuteriopropanoyloxy)propyl]-trimethylazanium;chloride Unlabelled CAS Number 119793-66-7 Product Data Storage Temperature -20C Shipping Temperature Room Temperature Product Type Stable Isotope Labelled

ACS2 is essential for growth and ACS1 is necessary for utilization of alternative carbon sources [33]

Its neuroprotective properties make it ideal for addressing age-related cognitive decline, while its ability to cross the blood-brain barrier sets it apart from other carnitine derivatives

Carnitine substitution resulted in an enhanced excretion of both, free carnitine and acylcarnitines, whereas acetylcarnitine accounts for 5065% of total acylcarnitines