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Patients with early-stage ALD often suffer from malnutrition or infections due to protein damage, so nutritional therapy should be implemented, focusing on providing high-protein, low-fat diets while balancing vitamin and folic acid levels within the body ( As ALD progresses to severe alcoholic hepatitis and cirrhosis, treatment guidelines recommend adding hormonal therapy to the early-stage treatments to prevent and halt the progression of cirrhosis

The Wnt/-catenin pathway, essential for cell proliferation, differentiation, and tissue regeneration, also becomes less active with age, leading to decreased skin regeneration and collagen synthesis

Pharmacokinetics of LR3-IGF-I in lambs

KPV is an anti-inflammatory tripeptide that modulates NF-B signaling [5] [6]

CABI Publishing: Wallingford, UK, p 256