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Description

Zhu J, Jiang X, Chang Y, Wu Y, Sun S, Wang C, Zheng S, Wang M et al (2023) Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement

R., Bower, R

The analysis integrates findings from preclinical investigations, limited clinical data, and regulatory perspectives

Treatments with DSIP and DSIP-CBBBP are shown to effectively increase melatonin levels, indicating a stress-mitigating potential, whereas CBBBP treatment alone does not significantly affect melatonin levels, pointing to its limited efficacy in this context