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10.1097/MOL.0000000000000377 29

Boyanova et al., 2023)

Most of these studies have been conducted with clinic-based populations that might be more prone to risk reduction and screening behaviors than those with a similar risk profile in the general population.[7] In terms of sun protection, in a Swedish population, 87 young adults with dysplastic nevi were surveyed, and 70% estimated their melanoma risk to be equal or lower than that of the Swedish population in general, and one third reported frequent sunbathing behavior.[8] Another study examined 229 first-degree relatives (FDRs) referred by melanoma patients attending clinic appointments

Secondly, they indicate that upon ATMi there is an increase in glucose-derived 13 C flowing through oxidative TCA cycle to Glu and GSH rather than promoting NADH and FADH2 production corresponding to the decrease in ETC activity indicated by OCR measurement (Fig