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doi: 10.1016/S0005-2736(01)00454-0

It also stated that elevated glutathione levels raised antioxidant levels and resistance to oxidative stress in cancer cells

Furthermore, we confirmed the expression of the full-length fusion hGrx1-roGFP2 protein with the predicted size of 47 kDa in parasite lysates of 3D7 (3D7 hGrx1-roGFP2 ) and Dd2 (Dd2 hGrx1-roGFP2 ) strains via western blotting (Fig

Phase 2: maintenance (ongoing) After the loading phase, transition to maintenance dosing

In hypoxic tumor microenvironments, hypoxia inducible factor 1 subunit alpha (HIF1A, also known as HIF1) represses DLAT expression and confers resistance to cuproptosis 176 , supporting the existence of a HIF1A-DLAT-GSH regulatory axis