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Drugs with high extraction ratios will show marked variations in bioavailability between subjects because of differences in hepatic function and blood flow

Disclosure of interest: None E-Posters - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.09 - SEX, GENDER AND STROKE P2325 - ESOC25-168 STROKE CARE IN WOMEN IMPROVED BY A PROTOCOLIZED NEURO-CARDIO PATHWAY: THE DiVERT STUDY David Z Rose 1 , Jana Braklow 2 , Krishna Pothineni 2 , Andrea Natale 3 , Frank Cuoco 4 , Darren Sidney 4 , Rawan Albadareen 5 , Bibhu Mohanty 1 , Marla Hairston 1 , Jessica Mikacevich 6 , Roberto Carta 6 , Noreli Carolina Franco 6 , Karah Neisen 6 , Dhanunjaya Lakkireddy 5 1 University South Florida, Tampa General, Tampa, United States, 2 Research Medical Center, Kansas City, United States, 3 St

10.1021/acs.biomac.3c00410 Biomacromolecules 85 HillB.ZakA.KheraE.WenF

It is believed that cortisol enters the saliva by passive diffusion or in other ways independent of active mechanism transports, the concentration of cortisol in saliva remains unchanged depending on the amount of saliva that is formed

It is also not known whether Bacteriostatic Water for Injection containing additives can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity