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Male and Female Results: How Sermorelin Affects Different Bodies While sermorelin works similarly in both men and women by stimulating natural HGH production, the before and after effects can present differently depending on sex-specific hormones, body composition, and goals

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What they found: Significant improvement in muscle insulin signaling (AKT/mTOR pathway) Increased expression of genes for mitochondrial biogenesis Increased expression of tissue remodeling Drop in HOMA-IR of ~25 % No adverse events Why it matters: This was the first high-quality randomized clinical trial of NMN in humans