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Subsequently, Western Blot (WB) analysis detected a decrease in total P53 expression but an increase in phosphorylated P53 (p-P53) expression in OGD-induced senescent endothelial cells post FOXO4-DRI treatment (Figures 5B,C)

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Cysteine availability is often the rate limiter for glutathione synthesis, and thus supplementing with NAC increases net glutathione levels, which is useful in disease states characterized by ischemia, increased oxidative stress, and reduced available glutathione [210, 211]

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Biological process (BP) over-representation analysis and Gene Set Enrichment Analysis (GSEA) were performed using Clusterprofiler (version 4.0.5) 58 and org.Ce.eg.db (version 3.13.0)

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If you see a biological effect hours after a single subcutaneous injection, it's critical to question the mechanism

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Buening-Fesel M, Rueckert-John J

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