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Medications: Some medications, such as proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2 blockers), and certain diabetes medications, can interfere with vitamin B12 absorption or increase the risk of deficiency over time

Control 65 , 378389 (2018)

However, analysis of 20% weight loss was not performed for the 0.3 mg and placebo groups because no participants in those arms achieved that degree of reduction [1]

Using monkeys as a model of human aging, researchers found that old monkeys have greater systemic inflammation as compared to young monkeys

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