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Nevertheless, although the cytochrome P450 pathway generates toxic species from trichloroethylene and tetrachloroethylene (Bull et al., 2002), a major contributor to the overall toxicity of trichloroethylene and tetrachloroethylene is the corresponding cysteine S -conjugate despite the fact that the glutathione S -conjugation pathway is quantitatively minor (Dekant, 2003)

(3) Yue X, Liu SL, Guo JN, Meng TG, Zhang XR, Li HX, Song CY, Wang ZB, Schatten H, Sun QY, Guo XP

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"Economic Effects of Environmental Crises: Evidence from Flint, Michigan"

Hambidge KM, Miller LV, Westcott JE, Sheng X, Krebs NF