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NogueiraCAlmeidaLSNestiCPezziniIVideiraAVilarinhoLet al

doi:10.1161/CIRCULATIONAHA.123.066485

With respect to the crosstalk between mitochondria and the endoplasmic reticulum (ER), they reported that mitochondria-associated ER membrane (MAM) disruption and mitochondrial Zn 2+ overload in senescent NPCs subjected to oxidative stress

After drug-induced Wnt activation in both damaged and undamaged tissues, cells located in the center and the periphery of the neuromasts (where supporting cells and mantle cells reside) are competent to respond by increasing mitotic events, ultimately resulting in enhanced hair cell regeneration (Head et al., Two recent studies (Jiang et al., 2014) examined the temporal expression of Wnt target genes and other components of the Wnt pathway in supporting cells and mantle cells in response to hair cell damage