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Ehara, M

Oral methotrexate in mice: a co-carcinogenic as well as an anti-tumor agent to methylcholanthrene-induced cutaneous tumors

FIGURE 3 The immunopharmacological effects of GSH are evident through several distinct but interconnected pathways, including regulation of inflammatory signaling networks like MAPK and NF-B, buffering of pathologic ROS as well as maintenance of cellular ROS signaling, and modulation of both peripheral and central immune cell activity (Bae et al., 2011