glutathione redox state Balanced Regulation of Status of Intracellular Thioredoxin Revealed by in-Cell NMR Redox-sensitive YFP sensors for monitoring

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Wuhan Science and Technology Major Project 2023020302020708

Silibinin also modulates mitochondrial dynamics by up-regulating DRP1, and down-regulating OPA1, MFN1, ATP content, and mitochondrial biogenesis regulatory factors (TFAM, PGC1 , and NRF2), which promotes both extrinsic and intrinsic pathways of apoptosis in breast cancer (MCF-7 and MDA-MB-231) cells [927]

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