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For example, phosphorylated p38 is translocated into the cell nucleus and upregulates cytokines/chemokines under oxidative stress

Ellis, J

de Vries, L

A 2023 meta-analysis found that NAC improved some metabolic markers in women with PCOS, including fasting glucose.21 More recent research has also explored NAC alongside ovulation-induction treatments, suggesting possible benefits for endocrine and reproductive outcomes.20 While the findings are encouraging, researchers are still working to determine which women are most likely to benefit and how NAC compares with established treatments such as metformin

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