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Figure 6 5.1 Antioxidants and ROS inhibitors Oxidative stress drives ferroptosis and contributes to the lung injury observed in ARDS

Research has shown that ferroptosis triggers and amplifies multiple inflammatory responses, enhances inflammation by releasing damage-associated molecular patterns, further activates immune cells, and significantly stimulates the expression of inflammatory cytokines, thus forming complex connections between inflammation and ferroptosis in psoriatic skin lesions [207]

Furthermore, emerging studies explore its role in next-generation combination peptide therapy research

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Nonetheless, environmental stressors like UV radiation, heat, or air pollution can cause a surge in ROS levels, potentially leading to significant cellular damage 34