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in this issue of Nature Metabolism show that CD38 expression in macrophages induced by senescence-associated inflammation accounts for the age-related decline in NAD + levels

However, these studies were constrained by the utilization of pooled-sample strategies, low throughput methods, or outdated platforms and technologies, which limited the scope of protein identification

Sidhu, A

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The SURMOUNT-5 trial later confirmed that tirzepatide produced 47% greater weight loss than semaglutide in a head-to-head comparison, solidifying its position as a leading option for weight management