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The Increlex label cites preclinical 2-year rat carcinogenicity studies in which increased mammary and skin tumor incidence occurred at high IGF-1 exposure

Illum, 2003

B12 injections may also be indicated in those with pernicious anaemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

Localized Treatment : Targeting the problem area directly, ICP minimizes systemic side effects and does not interfere with other ongoing treatments