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Citation2 For example, in skeletal muscle, the accumulation of senescent cells has been linked to sarcopenia, the age-related loss of muscle mass and function

As the disease progresses and compensatory mechanisms fail, BDNF levels drop significantly

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Notably, the G/D-CuP group demonstrated the lowest CD86/CD206 ratio, further indicating a promoted transition from the M1 to M2 phenotype (Supplementary Fig