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doi: 10.1016/j.cmet.2007.11.006

FGF21 is characterized by anti-inflammatory, anti-oxidative stress properties with its circulating concentration increasing during periods of muscle activity or critical stress (239)

Gclc fl/fl mice were described previously 127 and were crossed to Mb1-Cre + expressing mice 46 to obtain the Gclc fl/fl Mb1-cre strain

(See Effects of temperature on photosynthesis) Water : Excess of water (flooding leading to root asphyxia) Lack of water causing droughts (See Water needs of plants : how to satisfy them ?) Solar radiation : excess of light, UV (See Cellular impact of solar UV rays) Nutrient deficiencies : mineral elements (especially magnesium), nitrogen Soil salinity : excess of sodium and chlorine ions (See focus on Land salinization) Soil pollution : heavy metals (cadmium, lead, mercury, copper, aluminum, ) Atmospheric pollution : (See What is the impact of air pollutants on vegetation?) Primary pollutants: sulfur dioxide (SO 2 ), nitrogen oxides (NO x ), ammonia (NH 3 ), volatile organic compounds (VOC) Secondary pollutant: ozone (O 3 )

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