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Previously, we performed microarray analysis on livers from Cpt2 L/ mice following a 24-hour fast and demonstrated an induction of Atgl mRNA (12)

Rabbits challenged with high concentrations of BFT show tissue damage and hemorrhage, an increase in IL-8 expression, NF-B activation, and disruption of the epithelial barrier ( BFT was the first bacterial effector reported to activate the -catenin-dependent gene expression ( c-Myc expression and cellular proliferation in the APC mutant cell lines HT29/C1 and SW480 ( destruction complex is a condition needed for BFT to induce -catenin-mediated effects

This fungus adheres to damaged epithelial surfaces, exploiting disruptions caused by conditions such as gastroesophageal reflux disease and Barretts esophagus, both of which are precursors to esophageal adenocarcinoma