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Neelakantan et al., Biochemical Pharmacology, 2018, gave diet-induced obese mice the compound and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with food intake unchanged (PMID 29155147) [3]

and the real relationship between targeted CD38 therapy and the efficacy of PD-1/PD-L1-targeted therapy

The FDA subsequently classified AOD-9604 within Category 2 of the bulk drug substance review process, and the compound was later withdrawn from that nomination in April 2026

This is why our commitment at Real Peptides to small-batch synthesis and rigorous third-party testing is so vital

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